Both teams came into the game with injuries, but the 49ers were missing more as Christian McCaffrey has yet to begin his season, Brandon Aiyuk is likely slated to miss time with the injury he suffered on Sunday, and Deebo Samuel was a nonfactor in the game as he did not register any stats.

After the game, head coach Kyle Shanahan shared why Samuel left the game early.

“Throat, stomach things, just real fatigued,” Shanahan said. “Struggled to breathe, couldn’t catch his breath … he kept trying to fight through it, but once he was struggling with the breathing and everything, we had to shut him down.”

Samuel will most likely be able to play against the Dallas Cowboys next week.